A new, non-invasive system has been developed by a team of researchers from NYU Abu Dhabi (NYUAD), to facilitate the diagnosis and treatment of gastrointestinal motility disorders. The researchers led by Khalil Ramadi, Assistant Professor of Bioengineering at NYUAD have generated 3D magnetic field gradients using high-frequency electromagnetic coils that encode each spatial point with a distinct magnetic field magnitude, to track the movement of an ingestible “smart pill” through the Gastrointestinal (GI) tract. The field magnitude is measured and transmitted by the “smart pill” to determine its precise location, which is then communicated to a smartphone using Bluetooth technology.
Existing 'smart pills' do not offer the large field-of-view (FOV), high spatial resolution, and fully wireless operation that the 3D magnetic field gradient developed by the researchers allows for. This new technology holds the potential for future use in clinical applications such as more accurate and efficient diagnosis of gastrointestinal disorders and the precise targeting of therapeutic interventions and minimally-invasive procedures.
The ingestible wireless device senses and transmits its local magnetic field to an outside receiver. The magnetic field is applied by electromagnets that can be incorporated into backpacks and jackets for a more realistic assessment of GI motility, the movement of food from the mouth through the pharynx (throat), esophagus, stomach, small and large intestines a, and out of the body, as patients go about their lives. This system was successfully modelled in the gastrointestinal systems of large animals. The findings are reported in the paper titled “Location-aware smart-pills for wireless monitoring of gastrointestinal dynamics,” published in the journal Nature Electronics.
